There was investigated the opportunity of niobium separation from titanium, tantalum, and other associated components by liquid-liquid extraction from solutions originating from the loparite concentrate hydrochloric treatment without addition of fluoride-ion at the extraction and stripping stages. Extraction possibilities of different industry extractive agent and their mixtures have been investigated. Comparative data of titanium, niobium, tantalum behaviors in extraction process with different concentrates of hydrochloric acid. The sample of niobium pentoxide with the content of impurity elements of ≤ 0,1% was obtained.