The complex of researches of ion-change extraction, separation and concentration of molybdenum and rhenium applying to nitratesulphuric acid media from leaching of molybdenum concentrates has been realized. Relationships of molybdenum and rhenium sorption and desorption in static and dynamic conditions have been obtained and optimal technological parameters of researched processes have been defined. Complex ecological safe technology of hydrometallurgical processing of molybdenum concentrates with obtaining of pure compounds of rhenium and molybdenum and accompanied extraction of other valuable components and regeneration of chemical reagents has been developed.